Seventeen-year-old Angelina Dunbar learns from her adoptive parents, Derek and Sharon, about her brutal history, and of her heritage as a Mighty One referred to in Genesis 6. As the hybrid child of a human mother and fallen angel, Angelina will live forever in perfect health, with a beautiful body, and the power to influence others.

Longing only for normalcy, she lives with her parents in seclusion, hiding from those who would consider her a freak. Riddled with guilt over the death of her childhood friend, she seeks redemption, risking exposure by using her gifts as a champion for others.

Now, as Angelina stands at the threshold of adulthood, the demon responsible for her eternal youth and beauty demands a terrible payment - the annihilation of humankind. Accompanied by mysterious, Krikor, and armed with the ancient talisman, Nino, Angelina travels to the cradle of civilization to make her stand.